The dried powder of premna latifolia was used to treatment the epilepsy in different doses of ethanolic extract (200 mg/kg, 600 mg/kg and 800 mg/kg) and Phenytoin (20mg/kg) as standard drug in experimental animal models like, Maximm electric shock test in mice, pentylene induced convulsions in mice, from all the experimental model results were observed that the premna latifolia was possess the dose dependent anticonvulsant activity and significantly controlled the seizures of all stages in mice. The present study conclded that the effectiveness of the plant�s extract in the experimental convulsion used probably suggests that the plant could be used in both Petitmal and Grandmal types of epilepsy.
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